Clostridium difficile Infection News

• ACG 2022 RBX2660 Shows Promise in Breaking the Cycle of Recurrent C diff Building on the success seen with fecal microbiota transplantation, this experimental treatment lowered the rates of recurrent C difficile infections.
  Medscape Medical News, October 27, 2022
• IDWeek 2022 C. Diff Recurrence Drops With Highly Targeted Ridinilazole Phase 3 study results show the highly specific antibiotic was safe and effective and particularly effective in patients not taking another antibiotic.
  Medscape Medical News, October 20, 2022
• UEG 2022 FMT in IBS: 'We've Been Targeting Wrong Part of the Intestine' When administered to the small, rather than the more commonly used large, intestine, fecal microbiota transplantation results in sustained and better response rates in IBS, according to a new study.
  Medscape Medical News, October 14, 2022
• FMT Plus Anti-Inflammatory Diet Induces Remission in UC: Study In this more practically applicable study, the dietary intervention could be continued for a longer period, one expert observed.
  MDedge News, October 13, 2022
• Early FMT Shows Promise for Preventing Recurrent C difficile The results of this trial suggest that microbiota restoration might be necessary to obtain sustained resolution following C difficile infection.
  MDedge News, October 06, 2022
• Your Poop May Hold the Secret to Long Life Making a deposit to a "poop bank" sounds gross, but it could be a key step in ensuring your own long-term health for years to come.
  WebMD Health News, September 13, 2022
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• Fecal Transplant Treatments Might Transmit Monkeypox: FDA It’s not known whether the monkeypox virus can be transmitted through feces, but the agency advised additional safety precautions, including donor screening.
  Medscape Medical News, August 25, 2022
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• Fecal Transplant Trial for IBS Shows Lasting Response Investigators also find that changes in 10 bacteria were significantly correlated with IBS symptoms.
  Medscape Medical News, July 06, 2022
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• C. diff: How Did a Community Hospital Cut Infections by 77%? It took teamwork by a wide range of professional staff and support from leadership.
  Medscape Medical News, May 26, 2022
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• DDW 2022 Fidaxomicin Favored Over Vancomycin in Real-World C diff Study Researchers compared the agents for treating both initial and recurrent Clostridioides difficile infections in a Medicare population.
  Medscape Medical News, May 24, 2022
• DDW 2022 Bacterial Cocktail, Spores Counter Recurrent C difficile Both the complex mixture and specific, refined spores may hold promise in reducing recurrences, and may circumvent fecal microbiota transplants.
  Medscape Medical News, May 24, 2022
• Understanding Toxin Testing Results for C diff Testing stool samples for C difficile exotoxins A and B is frequently used to diagnose a C difficile infection, but clinicians need a greater understanding of what the results mean.
  Medscape Medical News, May 06, 2022
• Novel Antibiotic Shows Promise for C diff Infection A novel antibiotic therapy for Clostridioides difficile infection, currently dubbed CRS3123, has demonstrated narrower selectivity and reduced bacterial derangement in the gut compared with other antibiotics.
  Medscape Medical News, May 06, 2022
• Black, Senior Patients More Likely to Get Unneeded Antibiotics A new study that looked at 7 billion trips to healthcare centers found that antibiotics continue to be far overprescribed, especially among Black and senior patients.
  WebMD Health News, April 20, 2022
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• Asymptomatic C. difficile Carriers May Infect Their Families Hospitalized asymptomatic C. difficile carriers may infect people they live with after they return home, new research suggests.
  Medscape Medical News, April 13, 2022
• Engineered Bacteria Could Protect Gut from Antibiotics: Study 'The problem comes when interventions such as medications or particular kinds of diets affect the composition of the microbiota and create an altered state, called dysbiosis.'
  WebMD Health News, April 13, 2022
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• What's the Future of Microbiome Therapies in CDI, Cancer? Preventive treatments for C difficile recurrence are in phase 3 trials. Oncologists are also investigating microbiome-based differences in treatment response.
  Medscape Medical News, March 18, 2022
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• Aerosolized Hydrogen Peroxide Can Significantly Reduce C. difficile Infections Aerosolized hydrogen peroxide is a new tool in fighting C. difficile in healthcare settings.
  Medscape Medical News, March 18, 2022
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• Are 'Antibiotic Diets' Good Practice? Researchers are debating whether probiotics and microbiome-boosting foods can help our guts recover during periods of antibiotic use, allowing patients to stay on course with treatment.
  Medscape Medical News, March 16, 2022
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• C difficile Vaccine: CLOVER Trial Shows Mixed Results There's mixed news from Pfizer on results from the CLOVER trial of their candidate vaccine for preventing C diff infection.
  Medscape Medical News, March 08, 2022
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