First Look

• High Maternal BMI Ups Risk of Fetal Congenital Heart Defects A Danish registry study of prenatal and postnatal data support the importance of advising women that a high BMI is a risk factor for congenital malformations, and obstetric and perinatal complications.
  First Look, July 11, 2023
• Metformin, SGLT2is Link With Longer T2D Survival Treatment with metformin or an agent from the SGLT2 inhibitor class linked with significantly better survival in people with type 2 diabetes in UK Biobank data.
  First Look, June 12, 2023
• 22% of US Adults With Diabetes Don't Know Their A1c Level In a representative sample of US adults with diabetes, 22% did not know their A1c level. The data were from more than 2700 people evaluated from 2013–2020 by the NHANES program.
  First Look, June 05, 2023
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• Impaired Thyroid Hormone Sensitivity Linked to Cancer Risk Decreased thyroid hormone sensitivity significantly linked with higher risk for papillary thyroid carcinoma in a single-center, retrospective study of 1594 Chinese patients during 2020.
  First Look, May 30, 2023
• Dietary Fiber Cut Gestational Diabetes, Preterm Birth A fiber supplement during pregnancy in high-risk women cut the incidence of gestational diabetes and preterm delivery in a single-center randomized study with 295 women.
  First Look, May 22, 2023
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• Colon Cancer Risk Quadruples Within Year of Appendicitis The investigators say acute appendicitis is likely an early warning sign for colon cancer, not a cause of it. The study covered was published as a preprint and has not yet been peer reviewed.
  First Look, May 22, 2023
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• Simple Insulin Sensitivity Score Stratifies Post-CABG Risk A simple-to-obtain measure of insulin resistance can stratify cardiac risk in patients who have undergone coronary artery bypass graft surgery to better guide follow-up care.
  First Look, May 10, 2023
• Metformin Ups Myocardial Perfusion and Survival in T2D Treatment of adults with type 2 diabetes with metformin significantly linked with better myocardial perfusion and improved survival in a multicenter, observational study with 572 subjects.
  First Look, May 09, 2023
• AI Improves Mammography Accuracy, Reduces Workload The first large, randomized trial on the issue supports integrating AI triage into mammography screening programs. The study was published as a preprint and has not yet been peer reviewed.
  First Look, May 08, 2023
• High Follistatin Predicts Poor Cardiometabolic Outcomes Elevated plasma levels of the liver protein follistatin may predict incident chronic kidney disease and other adverse outcomes, independent of diabetes, based on 23-year follow-up of a Swedish cohort.
  First Look, May 08, 2023
• Cortisol From Adrenal Masses Linked With Dysglycemia People with type 2 diabetes and a cortisol-secreting adrenal mass had worse glycemic control compared with those with type 2 diabetes and a nonfunctioning adrenal mass.
  First Look, May 04, 2023
• Depression After T2D Diagnosis Links With A1c Variability Adults diagnosed with clinical depression after type 2 diabetes onset had more A1c variability compared with people with type 2 diabetes and no depression or with depression predating their diabetes.
  First Look, May 03, 2023
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• Erectile Dysfunction Prevalence Spikes in Hyperthyroid Men Men with hyperthyroidism had a significantly higher prevalence of erectile dysfunction compared with similar men without hyperthyroidism in a meta-analysis of four studies.
  First Look, May 02, 2023
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• No Survival Benefit With NAC for Advanced Stomach Cancer Neoadjuvant chemotherapy did not improve survival in elderly patients undergoing gastrectomy for advanced gastric cancer. The study was published as a preprint and has not yet been peer reviewed.
  First Look, April 21, 2023
• Pricey Diabetic Foot Ulcer Products Can't Beat Standard Care Diabetic foot ulcer healing occurred at the same rate with standard wound care, standard care plus acellular matrix, or standard care plus cellular matrix in a randomized study with 117 patients.
  First Look, April 21, 2023
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• Stand-Alone FIT Screening Poor Predictor of CRC Risk But incorporating age and anemia status into FIT screening vastly improved risk prediction. The study was published as a preprint and has not yet been peer reviewed.
  First Look, April 19, 2023
• Prenatal Smoking Linked to Less Childhood T1D Risk Maternal smoking significantly linked with a lower risk for incident type 1 diabetes in children, but not in adulthood. Smoking by young adults showed a signal for a link to incident type 1 diabetes.
  First Look, April 18, 2023
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• EVOO as Main Dietary Fat Diet Improved Biomarkers Adults with obesity and prediabetes who used extra virgin olive oil as their primary dietary fat had improved inflammatory and oxidative-stress biomarkers in a controlled, prospective study.
  First Look, April 17, 2023
• Carnosine Cut OGGT Glucose Levels in Prediabetes and T2D Carnosine supplementation reduced glucose levels during an oral tolerance test but didn't affect insulin nor body mass index. Carnosine's safety and low cost make it attractive for further testing.
  First Look, April 13, 2023
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• AF Catheter Ablation Shown Safe, Effective Despite Obesity Catheter ablation for atrial fibrillation (AF) was safe, improved quality of life, and cut the AF burden regardless of body mass index in a large, single-center, prospective registry with 5841 patients.
  First Look, April 10, 2023