Diabetes & Endocrinology News

• Older Adults Want Medicare, Insurance to Cover Obesity Drugs Older adults with overweight or diabetes are especially eager to have coverage for weight-loss medications.
  Medscape Medical News, December 29, 2023
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• Light Activity in Childhood May Lower Cholesterol Light physical activity may be a crucial intervention target to attenuate the risk for elevated lipid levels and their sequelae in the pediatric population, study said.
  Medscape Medical News, December 29, 2023
• Sustained Weight Loss Linked to Lower Renal Risk in Diabetes Researchers report an independent inverse link between time spent within a target body weight range and composite kidney outcomes in individuals with overweight/obesity and type 2 diabetes.
  Medscape Medical News, December 28, 2023
• AHA Names Top CVD Advances for 2023 Advances in stroke, a novel antihypertensive, and new evidence that diabetes drugs may offer CVD benefits for those without diabetes are among the top developments in 2023, on the AHA's annual list.
  Medscape Medical News, December 28, 2023
• For Weight Loss With a Low-Carb Diet, Quality Matters Only low-carbohydrate diets that emphasized high-quality protein, fat, and carbohydrates from whole grains and other plant-based foods were associated with less weight gain.
  Medscape Medical News, December 27, 2023
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• 'Real-time Experiment': Compounded GLP-1s on Coupon Site Purveyors on coupon sites like Groupon are marketing weight loss programs that include compounded semaglutide and tirzepatide.
  Medscape Medical News, December 26, 2023
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• Europe: Erythritol Laxative Effect, Lead Levels Concerning A new evaluation by the European Food Safety Authority has set a new level for safe consumption of the sweetener while confirming that a warning label will still be necessary.
  Medscape Medical News, December 22, 2023
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• Walking Fast May Help Prevent Type 2 Diabetes An analysis indicates that patients with fairly brisk walking are at a 24% lower risk for type 2 diabetes than those with easy or casual walking.
  Medscape Medical News, December 22, 2023
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• Alert FDA Issues Warning About Counterfeit Ozempic The FDA has seized thousands of counterfeit units of semaglutide.
  Medscape Medical News, December 22, 2023
• GLP-1s, Antidiabetic Medications Show Safety in Pregnancy New research shows use of the drugs in pregnancy is on the rise, particularly in the United States, and although teratogenic risks appear low, limitations are notable.
  Medscape Medical News, December 22, 2023
• Can a Healthy Gut Microbiome Prevent Kidney Stones? Patients with kidney stones show key alterations in gut and urinary microbiota compared with those without.
  Medscape Medical News, December 22, 2023
• How an Obesity Drug Could Help Alcohol Use Disorder Promising preclinical and early clinical data suggest a role for GLP-1 receptor agonist therapy in treating alcohol use disorder.
  Medscape Medical News, December 21, 2023
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• Many Patients With Type 2 Diabetes Stop Meds After a Year Often, patients with type 2 diabetes on second-line medication discontinue their therapy within a year, warn US researchers who highlight the need for new prescribing approaches.
  Medscape Medical News, December 21, 2023
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• US FDA Approves Sweden-based Calliditas' Kidney Disease Drug The U.S. Food and Drug Administration (FDA) granted full approval to Swedish drugmaker Calliditas Therapeutics' drug to treat rare kidney disease IgA Nephropathy (IgAN), the...
  Reuters Health Information, December 20, 2023
• French Drugmaker Servier Ordered to Pay $471 Million for Mediator Scandal Drugmaker Servier must pay more than 430 million euros ($471 million) in connection with weight-loss pill Mediator, a French court ruled on Wednesday, saying the company was...
  Reuters Health Information, December 20, 2023
• Thyroidectomy Beneficial but Risky for Hashimoto Disease Unconventional approach leads to improved general health scores but "unacceptably high" 14% complication rate.
  Medscape Medical News, December 20, 2023
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• Obesity Associated With More Severe MIS-C Outcomes Clinicians should consider obesity as a comorbid factor at the clinical presentation of children with MIS-C, according to researchers.
  Medscape Medical News, December 20, 2023
• Users of Weight Loss Drugs Regain Weight After Stopping Use The research examined users of weekly injections of tirzepatide, which is the active ingredient in Eli Lilly and Co.'s Zepbound.
  WebMD Health News, December 19, 2023
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• Where Is the 'Microbiome Revolution' Headed Next? Famed microbiome researcher Dr Martin J. Blaser shares what he sees as the most promising applications, and the rigorous clinical trials needed to realize them.
  Medscape Medical News, December 19, 2023
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• GLP-1 RAs Associated With Reduced CRC Risk in T2DM The effects were more profound in patients with overweight and obesity in addition to diabetes.
  Medscape Medical News, December 19, 2023
• AANEM 2023 Novel Myasthenia Gravis Therapies Bring Opportunities New treatments for myasthenia gravis are bringing new promise to patients, but their use must be balanced against short-term and long-term risks.
  MDedge News, November 27, 2023
• Novo to Launch Wegovy in Asia With February Roll-Out in Japan Novo Nordisk will launch its hugely popular anti-obesity drug in Japan on February 22, its first launch in Asia, even as it struggles to keep up with demand in existing markets.
  Reuters Health Information, November 23, 2023
• Novo Invests $2.3 Billion in France for Obesity Drug Production Novo Nordisk has announced a $2.3 billion investment to boost production of its wildly popular weight-loss and diabetes drugs at a site in Chartres, France.
  Reuters Health Information, November 23, 2023
• Cyberattacks Challenge Canadian Health Information Systems A new analysis recommends a four-stage plan for physicians and health systems to improve their cybersecurity practices.
  Medscape Medical News, November 27, 2023
• Metoclopramide Nasal Spray Eases Gastroparesis in Women A nasal spray formulation of metoclopramide was well tolerated and reduced symptoms of diabetic gastroparesis in women with moderate to severe baseline symptoms in a phase 3 study
  Medscape Medical News, November 27, 2023
• Novo Rations Ozempic Starter Kits Novo Nordisk will ration starter kits of Ozempic in Europe and reduce supplies of another diabetes drug, Victoza, to prioritize producing Ozempic.
  Reuters Health Information, November 21, 2023
• Medtronic Shrugs Off Concerns Over Newer Weight-Loss Drugs Medtronic raised its annual earnings forecast on Tuesday as strong sales in its surgical and diabetes units allayed concerns about the impact of new diabetes and weight-loss drugs on long-term growth.
  Reuters Health Information, November 21, 2023
• WCN 2023 A Role for Neurologists in Diabetic Peripheral Neuropathy The rise in diabetic neuropathy over the last few decades has paralleled the obesity and related diabetes pandemics, one expert says, and neurologists have a role to play in controlling it.
  Medscape Medical News, November 21, 2023
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• AHA 2023 Promising First Results With DNA Editing to Lower LDL The first-in-human HEART-1 trial of in vivo DNA editing called VERVE-101, shows reductions in LDL and PCSK9 protein in patients with familial hypercholesterolemia.
  MDedge News, November 21, 2023
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• Study Confirms Link Between Red Meat and Diabetes Risk The findings support the current dietary recommendations of limiting consumption of red meat and highlight the importance of alternative sources of protein, according to the researchers.
  Medscape Medical News, November 21, 2023
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• Placental Cell Disruption Tied to Adult Depression, CVD Disruption of placental Hofbauer cell function caused by prenatal infection or preterm birth may increase the risk for depression and cardiovascular disease in adulthood.
  Medscape Medical News, November 21, 2023
• How Should We Screen Transgender Patients for Cancer? The risk of cancer is not eliminated with gender transition, and the methods of screening should be adapted, say experts.
  Medscape Medical News, November 21, 2023
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• Differences in Twins Suggest Obesity Veers From Genetics When twins have significant differences in body mass index, the higher BMI more commonly veers from the genetically predicted BMI.
  Medscape Medical News, November 21, 2023
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• Choosing the Right Approach to Cancer and Menopause Symptoms Hormone replacement therapy may be considered to lessen these symptoms, but only in certain conditions, said a gynecologist.
  Medscape Medical News, November 21, 2023
• Circadian Calorie-Burning Cycles Altered in Obesity Among people with obesity, the lowest point of energy expenditure is not during sleeping hours, as seen in those without obesity.
  Medscape Medical News, November 21, 2023
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• PREVENT: AHA's New Risk Calculator Incorporates CKM Health The new cardiovascular disease risk equations start at age 30, include measures of kidney and metabolic health, add heart failure, and remove race from the equations.
  Medscape Medical News, November 20, 2023
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• Already-Available Drug Could Help Treat Type 1 Diabetes The ornithine decarboxylase inhibitor α-difluoromethylornithine, used to treat African sleeping sickness and unwanted hair growth, may also protect β cells of people with new-onset type 1 diabetes.
  Medscape Medical News, November 20, 2023
• Alert FDA OKs Symplicity Renal Denervation System for Hypertension After a mixed FDA panel review in August, the agency has approved Medtronic's Symplicity Spyral renal denervation system for treatment of hypertension.
  Medscape Medical News, November 20, 2023
• What’s Behind the Scramble for Semaglutide? Demand for a diabetes medicine called Ozempic is soaring as people take it to shed pounds, leading to shortages in countries including Britain, Germany, Belgium and the United States.
  Reuters Health Information, November 18, 2023
• Manufacturer Lonza Says It Will Not Fill Obesity Drug Syringes Lonza's chairman has ruled out plans to use its capacity to fill syringes and provide final production steps for new obesity drugs even as rivals scramble for a share of the booming weight-loss market.
  Reuters Health Information, November 17, 2023