"He even makes the deaf hear and the mute speak." [Mark 7:37]
I was privileged as a young scientist to lead a team that helped develop the modern cochlear implant, which (in several different forms) has restored hearing to approximately 800,000 formerly profoundly deaf individuals.
The crude information representing language sounds that cochlear implants deliver to the brain through stimulation of surviving auditory nerve fibers is sufficient for the remarkable plastic machinery of our brains to ultimately reinterpret it as normal-sounding speech.
Michael Merzenich, PhD
But what about the large population of individuals who can hear speech, but are unable to verbally respond? Such mute individuals fall into two large classes. Many have endured brain injuries that have physically destroyed speech production abilities in their brains. In others, the cortical speech production "machinery" is intact, but because of physical injury to the vocal tract (from cancer, trauma, or brainstem injury), the tract is neurologically dysfunctional. Nearly 20 years ago, I met a young child — let's call her "Katy" — who was a delightful sprite in my extended family. Near her fourth birthday, a nanny focused on watching her baby sister while Katy was playing on a playground slide with her jump rope.
COMMENTARY
Behind the Tech to Restore Voice, Expression in ALS and Beyond
Michael Merzenich, PhD
DisclosuresNovember 08, 2023
"He even makes the deaf hear and the mute speak." [Mark 7:37]
I was privileged as a young scientist to lead a team that helped develop the modern cochlear implant, which (in several different forms) has restored hearing to approximately 800,000 formerly profoundly deaf individuals.
The crude information representing language sounds that cochlear implants deliver to the brain through stimulation of surviving auditory nerve fibers is sufficient for the remarkable plastic machinery of our brains to ultimately reinterpret it as normal-sounding speech.
Michael Merzenich, PhD
But what about the large population of individuals who can hear speech, but are unable to verbally respond? Such mute individuals fall into two large classes. Many have endured brain injuries that have physically destroyed speech production abilities in their brains. In others, the cortical speech production "machinery" is intact, but because of physical injury to the vocal tract (from cancer, trauma, or brainstem injury), the tract is neurologically dysfunctional. Nearly 20 years ago, I met a young child — let's call her "Katy" — who was a delightful sprite in my extended family. Near her fourth birthday, a nanny focused on watching her baby sister while Katy was playing on a playground slide with her jump rope.
Credits:
Lead image: UCSF from https://www.youtube.com/embed/iTZ2N-HJbwA?si=7fidWgtL2eyVYcsz with permission
Image 1: Michael Merzenich, PhD
Medscape Neurology © 2023 WebMD, LLC
Any views expressed above are the author's own and do not necessarily reflect the views of WebMD or Medscape.
Cite this: Behind the Tech to Restore Voice, Expression in ALS and Beyond - Medscape - Nov 08, 2023.
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Authors and Disclosures
Authors and Disclosures
Author
Michael Merzenich, PhD
Professor Emeritus, Department of Neuroscience, University of California San Francisco
Disclosure: Michael Merzenich, PhD, has disclosed the following relevant financial relationships:
Serve(d) as a director, officer, partner, employee, advisor, consultant, or trustee for: Posit Science Corporation; Stronger Brains Inc. Serve(d) as a speaker or a member of a speakers bureau for: Posit Science Corporation; Stronger Brains Inc.
Received research grant from: National Institutes of Health
Have a 5% or greater equity interest in: Posit Science Corporation; Stronger Brains Inc.
Received income in an amount equal to or greater than $250 from: Posit Science Corporation; Stronger Brains Inc.; National Institutes of Health