Drug Repurposing 'Fast Track' to New Medicines for Obesity, Diabetes Researchers developed a computer program to identify drugs that may treat type 2 diabetes and obesity. The program looks at drugs for other diseases that may work on the basis of genetic pathways used by known drugs to treat the conditions.
The scientists identified four pathways with known drug targets for type 2 diabetes and five with known drug targets for obesity.
For diabetes: Scientists identified palbociclib (used to treat breast cancer) and cardiac glycosides (used to treat heart failure and heart rhythm disorders), which might be repurposed to treat type 2 diabetes.
For obesity: Baclofen (a muscle relaxant) and carfilzomib (a chemotherapy) could potentially be used to treat obesity.
Other possibilities: Fostamatinib (used to treat thrombocytopenia), sucralfate (used to treat stomach ulcers), and regorafenib (used to treat cancer) might be used to treat both conditions.
Long COVID Experts: 'So Incredibly Clear What's at Stake' The prevalence of long COVID-19 should be a bigger factor in public officials' response to the ongoing pandemic, experts argue. That includes public health messaging, prevention, treatment, social assistance and healthcare reform, advocates say.
More than one third of people who contract COVID-19 have neurologic complications that develop or persist 3 months after infection, estimates show.
