Could a Vaccine Fix the Fentanyl Crisis?
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COMMENTARY

Could a Vaccine (and More) Fix the Fentanyl Crisis?

Robert Glatter, MD; Paul J. Christo, MD, MBA

Disclosures

September 27, 2022

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This discussion was recorded on August 31, 2022. This transcript has been edited for clarity.

Robert Glatter, MD: Welcome. I'm Dr Robert Glatter, medical advisor for Medscape Emergency Medicine. Today we have Dr Paul Christo, a pain specialist in the Division of Pain Medicine at Johns Hopkins University School of Medicine in Baltimore, Maryland, and host of the national radio show Aches and Gains on SiriusXM Radio, joining us to discuss the ongoing and worsening fentanyl crisis in the US.

Welcome, Dr Christo.

Paul J. Christo, MD, MBA: Thanks so much for having me.

Glatter: I want to begin with a sobering statistic regarding overdoses. There were over 107,000 overdose deaths in the US from 2020 to 2021, of which over two thirds involved the synthetic opiate fentanyl, based on recent data from the CDC.

Let's start by having you explain how deadly fentanyl is in terms of its potency compared with morphine and heroin.

Christo: Fentanyl is considered a synthetic opioid. It's not a naturally occurring opioid like morphine, for example, or codeine. We use this drug, fentanyl, often in the anesthesiawell. We've used it for many years as an anesthetic for surgery very safely. In the chronic pain world, we've used it to help reduce chronic pain in the form of a patch.

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